The Reasons Why You Need Fish Oil: Your Body Will Thank You
Anti catabolic properties of fish oil
Our muscles endure a constant process of breakdown and rebuilding. The states are also known as catabolic or catabolism and anabolic or anabolism. Nature took care of the things and made these two processes balanced so that we can maintain our muscle mass (or even increase it in the right conditions)
The breakdown of muscle protein happens when our body is exposed to some kind of stress – an illness (diabetes, cancer etc.) , physical stress (walking, running, weight lifting etc.) and diet induced weight loss. During these catabolic states, muscle breakdown exceeds the process of muscle building, so we lose muscle mass and strength.
Muscle protein catabolism is primarily caused by the ubiquitin-proteasome system. The fatty acid EPA found in fish oil significantly decreases the activity of this system.
During stress states cortisol, a powerful hormone, is also released. Cortisol is important for normal functioning, but too much of this catabolic hormone breaks down muscle very fast. Fish oil may help buffer the negative side effects of stress on the body by reducing cortisol levels (study).
Anabolic properties of fish oil
Besides reducing the catabolic processes in the body, fish oil also seems to promote muscle growth by increasing muscle anabolism. Recent studies showed that supplementing with 4g of fish oil for 8 weeks ( 1.86 g EPA and 1.5 g DHA), significantly increases the anabolic response of muscle protein synthesis to amino acids and insulin. This anabolic response was due to an increased activation of the mTOR/p70S6K signalling pathway, an integral control point for muscle protein anabolism.
The augmented anabolic response to amino acids and insulin was shown to be due to an increased activation of the mTOR/p70S6K signalling pathway, which is considered an integral control point for muscle protein anabolism and muscle cell growth. (link)